Sometimes you can't even change the start page on your internet browser, I mean you change it and then it's back. If this happens use those programs to locate the parasites and remove them. Look for viruses too, there are viruses which are installed and then open a lot more ad pages and all sorts of crap. Another trick is to restore the registry to a previous time but do that only as a last resort because some programs you didn't have before may need to be reinstalled. ( to restore registry open "run" type scanreg /restore )
But with the combination of registry cleaner, parasite remover, virus killer you should be alright.
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